Scalable Yielding of Highly Stable Polyelectrolyte-Coated Copper Sulfide Nanoparticles by Flash Nanoprecipitation for Photothermal-Chemotherapeutics

Photothermal-chemotherapeutic nanoparticles (NPs) are attracting increasing attention and becoming more widely used for cancer therapy in the clinic due to their noninvasiveness, notable tissue penetration abilities, and low systemic adverse effects. However, functional ligands are conventionally modified onto photothermal NPs to well stabilize the inorganic particles suffering from complex chemical modifications, low productivity, and batch-to-batch inconsistencies, and thus significantly restricting their clinical applications. Herein, flash nanoprecipitation (FNP) is taken advantage of to afford rapid and uniform mixing for generating local supersaturated CuS clusters for small and highly stable CuS NPs effectively stabilized by polyacrylic acid through a continuous strategy. It greatly reduces the complexity for CuS NPs synthesis and functionalization in a facile intensified mixing process. These as-synthesized particles are high-drug loading, scalable, and most importantly, it is easy to control their sizes and charges through external conditions. Toxicity and tumor inhibition experiments confirm the high cell toxicity and good suppression of tumor growth under near-infrared irradiation indicating a promising prospect of FNP in the large-scale and continuous yielding of highly stable and high-performing photothermal-chemotherapeutic NPs for cancer therapy.     

Chromaticity-tunable remote LuYAG: Ce phosphor-in-glass film on regular textured glass substrate for white light emitting diodes

All inorganic remote phosphor-in-glass film exhibits excellent properties in high power white light-emitting-diodes (WLEDs) thanks to their easy fabrication and thermal stability. Herein, fabrication of (Lu, Y)₃Al₅O₁₂: Ce³⁺ (LuYAG: Ce)phosphors embedded in borosilicate glass film by the conventional solid state reaction and spin coating technology has been reported. The introduction of Y³⁺ ions reduces the difference of relative growth rate along some directions in growth of LuYAG microparticles, yielding a finer grain with smooth edges. By adjusting the molar concentration of Y³⁺ ions in LuAG phosphor, a series of tunable broadband emission from green to yellow region is observed and maintains excellent thermal stability. Meanwhile, the decay curves of samples with different Y³⁺ are almost same. SEM images show that phosphor particles are homogenously distributed within the glass matrix and keep their original morphology, suggesting the phosphor-in-glass films were synthesized as expected. Finally, a simple WLEDs based on the films was constructed using the commercial blue chip. The correlated color temperature ranging from 4853K to 4627K and high color rendering index from 81.4–79.7 were obtained. Upon the different driving current, the chromaticity coordinates of as-fabricated film exhibit good light color stability. These results bring an inspiring insight to tune the luminescent performance for remote WLEDs.     

基于个性化推荐的农产品电子商务系统设计

在我国社会经济快速发展的大背景下,城市居民对于农产品的需求呈现出多样化的发展趋势,通过针对电子商务系统的合理化设计,实现个性化的农产品推荐,对于增加农村居民收入有着十分重要的意义.因此,本文详细介绍了基于个性化推荐的农产品电子商务系统的设计方案,旨在提高农产品的销售效率.     

Spinel CoFe2O4 /carbon nanotube composites as efficient bifunctional electrocatalysts for oxygen reduction and oxygen evolution reaction

In the development of fuel cells, it is the key to large-scale commercialization of fuel cells to rationally design and synthesize efficient and non-noble metals-based bifunctional electrocatalysts for oxygen reduction reaction (ORR) and oxygen evolution reaction (OER). In this paper, spinel CoFe₂O₄/carbon nanotube composites (CoFe₂O₄/CNTs/FA) were synthesized by solvothermal and calcination method. XRD, TEM, XPS and BET characterizations indicate that the addition of complexing agent fumaric acid can improve the crystal growth kinetics and morphology of CoFe₂O₄/CNTs nanohybirds. The as-synthesized CoFe₂O₄/CNTs/FA pyrolyzed at 500 °C have an outstanding bifunctional catalytic activity for ORR and OER with the potential of 1.62V (vs. RHE) at a current density of 10 mA/cm² and half-wave potential E_1/2 = 0.808V (vs. RHE) in alkaline electrolyte, respectively. It is obviously better than unloaded CoFe₂O₄ nanoparticles and commercial CNTs. CoFe₂O₄/CNTs/FA also exhibit better methanol tolerance ability and durability than commercial Pt/C and RuO₂ catalyst. This investigation broadens an idea of simple compounding of spinel with carbon-based materials to improve electrochemical properties.     

Surface generation mechanism of ceramic matrix composite in ultrasonic assisted wire sawing

Ceramic matrix composites (CMC) are highly required in many fields of science and engineering. However, the CMC parts always have poor surface finish. This study attempts to improve cutting performance of CMC material by combing the advantages of ultrasonic assisted cutting and diamond wire sawing. Cutting force, surface roughness, machined edge and tool wear are analyzed based on experimental results. It shows that the oscillatory movement of tool edges provides positive effect on particle ejection and residual material reduction. Ductile chip formation can be achieved due to the small tip radius of grits. Obvious decrease in cutting force, surface roughness and tool wear are obtained. Moreover, burrs, fuzzing and fracture are reduced. Meanwhile, both the surface characteristics and shape accuracy are significantly improved. These results provide a valuable basis for application of ultrasonic assisted wire sawing and understanding of CMC cutting mechanisms.     

阶梯管件的矫直方法研究

针对单弧度弯曲阶梯管件,采用三点过弯压力矫直的修正方式,根据材料弹塑性力学理论,基于双线性强化弹塑性材料本构关系,解析了考虑变截面处应力集中因素的阶梯管件变形过程,推导了矫直行程计算公式.利用有限元软件显示动力学分析的阶梯管件矫直模拟过程以及相应的矫直实验对模型的正确性进行了验证,仿真和实验结果表明,矫直后的阶梯管件具有直线度高,矫直效果好的特点.     

一种改进的特征匹配算法在碎片云测量建模中的应用

为满足超高速撞击典型Whipple防护构型的损伤评估需求,利用图像处理技术对碎片云序列阴影图像进行深入研究。使用超高速序列激光阴影成像仪得到三组不同实验条件下碎片云发展过程的高清阴影图像,分别对每组最具代表性的2帧进行图像处理分析;根据碎片云图像特点以及碎片运动特性,提出了一种改进的碎片二次特征匹配算法,该方法包含碎片粗定位、特征定义及初匹配和精确匹配三步策略;通过运用改进的匹配算法,对选取的相邻两帧图片完成碎片高效匹配,并提取匹配碎片的运动参数,进而分析碎片的速度分布和飞行角度分布,获取二次碎片云相关运动特性;得到三组实验各自的轨迹模拟图。根据得到的轨迹分析结果分别对三组实验的后板损伤进行估计,并通过与防护构型的实际损伤结果进行比较,验证了该方法的有效性。     

基于ISVD多级降噪和SVM的轴承故障诊断研究

在强噪声背景下难以提取出滚动轴承的故障特征，导致对轴承的故障诊断准确率不高，针对这一问题，提出了一种基于小波变换、改进奇异值分解多级降噪算法与支持向量机模型的轴承故障诊断方法。首先，采用小波降噪对滚动轴承的原始信号进行了初始降噪，消除了部分的随机噪声；然后，主要通过改进相空间矩阵重构方式，对该信号进行了改进奇异值分解二次降噪，并提出了新的奇异值有效秩阶次确定方法，利用峭度对一维信号提取方案进行了优化，并对其完成了降噪；最后，通过提取了10个有效特征，结合支持向量机在MATLAB中进行了仿真实验，分析了不同特征对轴承的故障诊断结果的影响，并将方法与其他方法进行了对比分析。研究结果表明：采用多级降噪算法降低了轴承工作状态下的背景噪声，使其故障特征频率更为明显；支持向量机分类诊断器的故障识别准确率达到98.3%,能够有效地识别轴承故障发生的位置和严重程度。     

电位滴定法测定氟化钠的含量

建立了一种电位滴定法测定氟化钠含量的方法。该方法采用氢氧化钠降解氟硅酸钠与硝酸镧作为滴定剂，以氟离子选择电极为测量电极，测定总氟含量；扣除氟硅酸钠含量，获得氟化钠含量。结果表明，加标回收率范围为99.02%～99.79%,RSD(n=9)为0.24%，样品测定准确度与精密度良好。该方法简化了前处理操作步骤，减少了目视判断终点带来的误差，降低试验过程的毒性，提高了氟化钠含量的检测效率，可作为《HG/T 5210—2017牙膏用氟化钠》补充分析方法。